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Työnimike: Scientist, Neuroimmunology & immunohistochemistry

Työnkuvaus:
We are looking for a scientist with proven track of experience in ex vivo molecular and cellular neuroscience.
The position requires expertise in immunology and immunohistochemistry in basic science and preferably drug discovery using preclinical models of CNS.
In this position you will be independently leading projects focusing to relevant ex vivo endpoints of efficacy in animal models, including e.g. PD, AD, MS and injury-triggered animal models.
You have a strong expertise in various types of ex vivo analysis and interpretation of biomarkers derived from preclinical in vivo models.
You have strong background e.g. in multiparameter flow cytometry, immunohistochemistry, cytokine profiling, supporting immune function assessment.
You are independently able to manage planning, coordination, supervision and execution of the ex vivo part of client projects
and ensuring the scientific excellence including data analysis and reporting of the results. Scientist will be working closely with other teams and clients.
In addition to client projects, scientist will be involved R&D activities including validations of new markers and assays to support ex vivo readouts.
Qualifications and Experience:
Higher education degree in biological science (MSc) with 3+ years of experience, preferably PhD degree
Pharmaceutical industry, Preclinical Contract Research Organization or academic post-doctoral experience will be an asset.
Good problem solving skills, ability to coordinate and prioritize
Scientific expertise with demonstrable understanding of ex vivo techniques and neuroimmunology as a component in CNS diseases
Understanding of key features of in vivo pharmacology studies and drug development process in neurology and psychiatry
Hands on experience in development, optimization and validation of immunohistochemistry targets in CNS tissues
Hands on experience in development, optimization and validation of multi-color flow cytometry, data analysis and troubleshooting using multiparametric data analysis
Experience in other immunological techniques like in vitro cell cultures, Luminex, ELISA, gene expression analysis (qPCR, QuantiGene Plex) will be an asset
Fluent oral and written English, excellent communication skills, interpersonal and teamwork abilities
Ability to mentor and train staff will be an asset

Head of Biomarker and Molecular Imaging Laura Tolppanen, 017-3680801

numberOfPosts: 1

euresFlag: 1

jobCategoriesCodes_0: http://data.europa.eu/esco/isco/C2131

positionTypeCode: directhire

contractTypeCodes_0: fulltime

Työnantajan nimi: Charles River DRS Finland Oy

source: TIVA